TY  -  JOUR
AU  -  Zi, Guangrong
AU  -  Zhu, Guofu
T1  -  Risk factors for ischemic heart disease in professional drivers: 
a meta-analysis
PY  -  2025
Y1  -  2025-07-01
DO  -  10.1728/4632.46425
JO  -  Medicina dello Sport
JA  -  Med Sport
VL  -  78
IS  -  3
SP  -  239
EP  -  247
PB  -  Il Pensiero Scientifico Editore
SN  -  1827-1863
Y2  -  2026/04/03
UR  -  http://dx.doi.org/10.1728/4632.46425
N2  -  Summary. Objective. To identify risk factors for ischemic heart disease (IHD) in professional drivers through a systematic review and meta-analysis. Methods. A comprehensive literature search was conducted across multiple databases, including CNKI, CBM, Wanfang Data, VIP, FMRS Medline, The Cochrane Library, PubMed, Embase, and Web of Science, for studies published from January 1, 1990, to December 31, 2024. Keywords such as “ischemic heart disease,” “coronary heart disease,” “myocardial infarction,” “driver,” and “risk factor” were used. Relevant case-control studies were included based on predefined criteria and quality assessed using the Newcastle-Ottawa Scale (NOS), with studies scoring ≥7 considered high quality for meta-analysis. Results. Eleven studies involving 95,791 cases and 29,621 controls were included. The meta-analysis revealed a significant association between the driving profession and an increased risk of IHD (OR = 1.85, 95% CI: 1.63-2.11). Drivers with hypertension (OR = 2.58), smoking (OR = 2.70), obesity (OR = 1.54), diabetes (OR = 1.77), physical inactivity (OR = 2.12), dyslipidemia (OR = 1.82), and occupational stress (OR = 2.31) all exhibited significantly higher risks of IHD. Conclusions. The driving profession is a significant risk factor for IHD. Drivers with chronic conditions, unhealthy lifestyles, dyslipidemia, and occupational stress face an elevated risk. Health interventions should focus on lifestyle changes, managing hypertension and diabetes, and reducing work-related stress.
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